Comparative Evaluation Of The Efficacy Of Neem And Tetracycline When Incorporated In A Local Drug Delivery System When Used As An Adjunct To Scaling And Root Planing A Clinico-Microbiological Study

Background: Antimicrobial agent has been effectively used systemically and locally in management of periodontal disease. Local drug has an advantage of higher antimicrobial concentration in subgingival site. Presently large number of herbal product researches in oral use in various from. The study researches neem extract when incorporated in LLD system used as adjunct to scaling and root planing. Methods: The study included a total of 15 patients having chronic periodontitis (7 males and 8 females) with an average age of 25-55 yrs. The subjects were assessed clinically for Plaque index, Gingival index, probing pocket depth and microbiologically for the subgingival bacteria counts of Porphyromonas gingivalis, Prevotella intermedia, Fusobacterium nucleatum, Aggregatibacter actinomycetemcomitans. All clinical parameters were assessed at baseline (0 days), 1 month and 3 months. Full mouth scaling and root planing was performed. 3 groups were made Group Ascaling and root planing, Group Bscaling and root planing along with placement of tetracycline fibers, Group Cscaling and root planing along with placement of neem fibers. The 3 selected non adjacent sites were randomly assigned to one of the groups. The test sites in group B & C received intra pocket placement of tetracycline & neem fiber respectively. Result: Results showed an reduction in the PPD, gingival index and plaque index as well as the counts of the bacteria in all three groups. Higher reduction was observed in both test groups as compared to control. Conclusion: Herbal extracts such as Neem extracts exhibited good antibacterial property, and was found to be marginally better though not statistically significant than commercially available tetracycline fibres.